@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R6T8NP9F-T skos:prefLabel "Nucleic Acid Synthesis Inhibitors"@en, "Inhibiteurs de la synthèse d'acide nucléique"@fr ; a mesh:Descriptor, skos:Concept . jvr:-C6Z9L054-3 skos:prefLabel "Sulfhydryl Compounds"@en, "Thiols"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-KVKLF2PK-D . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-RLGZ62D2-Z skos:prefLabel "Antimétabolites antinéoplasiques"@fr, "Antimetabolites, Antineoplastic"@en ; a mesh:Descriptor, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-WJFDLBW4-7 skos:prefLabel "Antimetabolites"@en, "Antimétabolites"@fr ; a mesh:Descriptor, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-J8LJNZTH-Z skos:prefLabel "Purines"@fr, "Purines"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-KVKLF2PK-D . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H8LJ47P7-S skos:prefLabel "Immunosuppresseurs"@fr, "Immunosuppressive Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PJW8XS09-D skos:prefLabel "Azathioprine"@fr, "Azathioprine"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-KVKLF2PK-D . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KVKLF2PK-D skos:altLabel "E7WED276I5"@en, "6-Mercaptopurine"@fr, "6-Mercaptopurine"@en, "6-Thiohypoxanthine"@en, "6112-76-1 (monohydrate)"@fr, "6112-76-1 (monohydrate)"@en, "6-Mercaptopurine Monohydrate"@en, "6-Thiopurine"@en, "1,7-Dihydro-6H-purine-6-thione"@en, "50-44-2 (6-Mercaptopurine)"@en, "50-44-2 (6-Mercaptopurine)"@fr, "6H-Purine-6-thione, 1,7-dihydro-"@en, "PKK6MUZ20G"@fr, "PKK6MUZ20G"@en, "E7WED276I5"@fr ; owl:sameAs ; mesh:allowableQualifier jvr:-FWD2BGQ0-9, jvr:-NFTHND7Q-8, jvr:-R3QWLHRG-V, jvr:-T9HQD7ST-J, jvr:-M63HSDM7-1, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-THHNVC7V-3, jvr:-W6SQV79N-S, jvr:-NHL3D2X0-S, jvr:-HQRFT0C6-B, jvr:-S0CS1X5R-5, jvr:-SBNWSM1T-R, jvr:-R0ZCQ8X6-J, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-TJHVZCRZ-0, jvr:-L6C0XPHT-4, jvr:-BT300B3G-Q, jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-H7K65Q8S-Z, jvr:-G4R176S9-J, jvr:-XV06LPML-W, jvr:-G30ZJ446-J ; skos:broader jvr:-J8LJNZTH-Z, jvr:-C6Z9L054-3 ; skos:inScheme jvr: ; skos:prefLabel "Mercaptopurine"@en, "Mercaptopurine"@fr ; skos:hiddenLabel "Purinethol"@en, "BW57323H"@fr, "BW-57-323H"@fr, "Puri-Nethol"@en, "Mercaptopurina Wellcome"@en, "Leupurin"@en, "Mecaptopurine Anhydrous"@en, "Purimethol"@en, "BW 57-323H"@en ; a mesh:Descriptor, skos:Concept ; mesh:pharmacologicalAction jvr:-RLGZ62D2-Z, jvr:-R6T8NP9F-T, jvr:-WJFDLBW4-7, jvr:-H8LJ47P7-S ; dc:created "1999-01-01"^^xsd:date ; dc:modified "2018-07-05"^^xsd:date ; skos:definition "An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia."@en ; dc:established "1985-01-01"^^xsd:date ; skos:narrower jvr:-PJW8XS09-D . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .