@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KBLWNJWG-6 skos:hiddenLabel "Nitrogen Mustard N-Oxide"@en, "Mechlorethamine N-Oxide"@en, "Mechlorethamine Hydrochloride"@en, "Mechlorethamine Oxide"@en, "Mitomen"@en, "Embichin"@en, "NSC-10107"@en, "NSC-10107"@fr, "NSC10107"@fr, "Cloramin"@en, "Nitrogranulogen"@en, "Caryolysine"@en, "Chlorhydrate de chlorméthine"@fr, "NSC-762"@fr, "NSC-762"@en, "Nitromin"@en, "Mechlorethamine Hydrochloride N-Oxide"@en, "Mustargen"@en, "NSC762"@fr, "Oxyde de chlorméthine"@fr ; a skos:Concept, mesh:Descriptor ; skos:inScheme jvr: ; mesh:pharmacologicalAction jvr:-RH7RGR6D-2, jvr:-G0CLGTTZ-V, jvr:-B0M82B13-N, jvr:-PCGD0J2R-7 ; mesh:allowableQualifier jvr:-CB30NGKB-3, jvr:-SBNWSM1T-R, jvr:-R3QWLHRG-V, jvr:-FWD2BGQ0-9, jvr:-NKM836P1-M, jvr:-W6SQV79N-S, jvr:-THHNVC7V-3, jvr:-D0F21513-5, jvr:-S0CS1X5R-5, jvr:-M63HSDM7-1, jvr:-G30ZJ446-J, jvr:-BT300B3G-Q, jvr:-L6C0XPHT-4, jvr:-NB0XHT3S-N, jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-T9HQD7ST-J, jvr:-G4R176S9-J, jvr:-NHL3D2X0-S, jvr:-Q3979798-W, jvr:-NFTHND7Q-8, jvr:-R0ZCQ8X6-J, jvr:-HQRFT0C6-B, jvr:-WK5F724J-1, jvr:-XV06LPML-W ; skos:altLabel "Chlorethazine"@en, "Methylchlorethamine"@en, "Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-"@fr, "Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-"@en, "302-70-5 (N-oxide, HCl)"@fr, "302-70-5 (N-oxide, HCl)"@en, "50D9XSG0VR"@fr, "50D9XSG0VR"@en, "51-75-2"@fr, "51-75-2"@en, "Bis(2-chloroethyl)methylamine"@en, "126-85-2 (N-oxide)"@fr, "126-85-2 (N-oxide)"@en, "Mustine"@en, "Chlormethine"@en, "Nitrogen Mustard"@en, "55-86-7 (HCl)"@fr, "55-86-7 (HCl)"@en, "L0MR697HHI"@fr, "L0MR697HHI"@en ; owl:sameAs ; skos:prefLabel "Mechlorethamine"@en, "Chlorméthine"@fr ; skos:broader jvr:-WQXMZ66C-2 ; dc:modified "2016-07-01"^^xsd:date ; skos:definition "A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA."@en ; dc:established "1963-01-01"^^xsd:date ; dc:created "1999-01-01"^^xsd:date . jvr:-G0CLGTTZ-V skos:prefLabel "Irritants"@fr, "Irritants"@en ; a mesh:Descriptor, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RH7RGR6D-2 skos:prefLabel "Antineoplastic Agents, Alkylating"@en, "Antinéoplasiques alcoylants"@fr ; a mesh:Descriptor, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-B0M82B13-N skos:prefLabel "Chemical Warfare Agents"@en, "Armes chimiques"@fr ; a mesh:Descriptor, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WQXMZ66C-2 skos:prefLabel "Moutardes à l'azote"@fr, "Nitrogen Mustard Compounds"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-KBLWNJWG-6 . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PCGD0J2R-7 skos:prefLabel "Agents alcoylants"@fr, "Alkylating Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .