@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-XVNGG6CP-7 skos:prefLabel "Tosyl Compounds"@en, "Composés tosyliques"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-K9P55PSB-7 . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-K9P55PSB-7 skos:inScheme jvr: ; skos:prefLabel "N-(5-Amino-1-chloroacétylpentyl)-para-toluènesulfonamide"@fr, "Tosyllysine Chloromethyl Ketone"@en ; skos:altLabel "2104-86-1"@fr, "2104-86-1"@en, "N-(5-Amino-1-chloroacétylpentyl)-p-toluènesulfonamide"@fr, "TLCK"@en, "N-(5-Amino-1-chloroacétylpentyl)-4-méthyl-benzènesulfonamide"@fr, "Tosyllysyl Chloromethane"@en, "Tosyl-lysyl chlorométhyl cétone"@fr, "1-Chloro-1-désoxy-Nalpha-tosyl-lysine"@fr, "1-Chloro-1-désoxy-Nalpha-tosyllysine"@fr, "Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-"@fr, "Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-"@en, "TLCC"@fr, "Nalpha-Tosyllysyl chlorométhyl cétone"@fr, "Chlorotosylamidoaminoheptanone"@en ; skos:definition "An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process."@en ; mesh:allowableQualifier jvr:-G4R176S9-J, jvr:-FWD2BGQ0-9, jvr:-HQRFT0C6-B, jvr:-CB30NGKB-3, jvr:-R0ZCQ8X6-J, jvr:-M63HSDM7-1, jvr:-THHNVC7V-3, jvr:-NHL3D2X0-S, jvr:-BT300B3G-Q, jvr:-G30ZJ446-J, jvr:-WK5F724J-1, jvr:-NFTHND7Q-8, jvr:-T9HQD7ST-J, jvr:-TJHVZCRZ-0, jvr:-S0CS1X5R-5, jvr:-NB0XHT3S-N, jvr:-XV06LPML-W, jvr:-L6C0XPHT-4, jvr:-SBNWSM1T-R, jvr:-W6SQV79N-S, jvr:-R3QWLHRG-V, jvr:-D0F21513-5, jvr:-H7K65Q8S-Z, jvr:-NKM836P1-M, jvr:-Q3979798-W ; skos:broader jvr:-LRRS3LHV-5, jvr:-XVNGG6CP-7 ; owl:sameAs ; mesh:pharmacologicalAction jvr:-PCGD0J2R-7, jvr:-Z9LB05R5-D, jvr:-B2VPSXX1-8 ; a skos:Concept, mesh:Descriptor ; dc:established "1991-01-01"^^xsd:date ; dc:created "1974-11-19"^^xsd:date ; dc:modified "2000-06-22"^^xsd:date . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9LB05R5-D skos:prefLabel "Inhibiteurs de la synthèse protéique"@fr, "Protein Synthesis Inhibitors"@en ; a mesh:Descriptor, skos:Concept . jvr:-B2VPSXX1-8 skos:prefLabel "Serine Proteinase Inhibitors"@en, "Inhibiteurs de la sérine protéinase"@fr ; a mesh:Descriptor, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-LRRS3LHV-5 skos:prefLabel "Chlorométhyl cétones d'acides aminés"@fr, "Amino Acid Chloromethyl Ketones"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-K9P55PSB-7 . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PCGD0J2R-7 skos:prefLabel "Agents alcoylants"@fr, "Alkylating Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .