@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z4G3RJKL-T skos:prefLabel "ATP-Binding Cassette Transporters"@en, "Transporteurs ABC"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-JVCPPN5G-K . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-QWLK6XPL-W skos:prefLabel "Protéine-2 associée à la multirésistance aux médicaments"@fr, "Multidrug Resistance-Associated Protein 2"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-JVCPPN5G-K . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L703SJ5P-F skos:prefLabel "Cystic Fibrosis Transmembrane Conductance Regulator"@en, "Protéine CFTR"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-JVCPPN5G-K . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-CSBZ36QP-8 skos:prefLabel "Transporteurs d'anions organiques ATP-dépendants"@fr, "Organic Anion Transporters, ATP-Dependent"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-JVCPPN5G-K . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-JVCPPN5G-K skos:altLabel "Protéines de la sous-famille C de cassette de liaison à l'ATP"@fr, "ATP-Binding Cassette, Sub-Family C Proteins"@en, "Multispecific Organic Anion Transport Proteins"@en, "MOAT Protein"@en, "Transporteurs multispécifiques d'anions organiques"@fr, "Protéines associées à MDR"@fr, "Multidrug Resistance-Associated Protein"@en, "Protéines associées à la résistance multiple aux médicaments"@fr, "Multispecific Organic Anion Transporter"@en, "Protéines associées à la résistance médicamenteuse multiple"@fr ; a skos:Concept, mesh:Descriptor ; dc:established "2002-01-01"^^xsd:date ; mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-L6C0XPHT-4, jvr:-NB0XHT3S-N, jvr:-TJHVZCRZ-0, jvr:-Z9TSGBXH-4, jvr:-G7KXQWSR-5, jvr:-T2TS0S41-N, jvr:-BT300B3G-Q, jvr:-THHNVC7V-3, jvr:-WZF2ZR3L-B, jvr:-T9HQD7ST-J, jvr:-NHL3D2X0-S, jvr:-N2WP45CN-V, jvr:-HQRFT0C6-B, jvr:-Q3979798-W, jvr:-XV06LPML-W, jvr:-CB30NGKB-3, jvr:-FWD2BGQ0-9, jvr:-S0CS1X5R-5, jvr:-SBNWSM1T-R, jvr:-H7K65Q8S-Z, jvr:-WK5F724J-1, jvr:-R0ZCQ8X6-J, jvr:-R3QWLHRG-V, jvr:-NFTHND7Q-8, jvr:-G30ZJ446-J, jvr:-CJXMKG5Q-F, jvr:-NKM836P1-M, jvr:-M63HSDM7-1, jvr:-D0F21513-5 ; skos:narrower jvr:-QWLK6XPL-W, jvr:-L703SJ5P-F ; skos:prefLabel "Protéines associées à la multirésistance aux médicaments"@fr, "Multidrug Resistance-Associated Proteins"@en ; skos:definition "A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 family of proteins."@en ; owl:sameAs ; skos:related jvr:-ZX5LF3BD-1, jvr:-WDNTVV9S-2 ; skos:inScheme jvr: ; skos:broader jvr:-Z4G3RJKL-T, jvr:-CSBZ36QP-8 ; dc:created "2001-07-25"^^xsd:date ; dc:modified "2018-07-13"^^xsd:date . jvr:-WDNTVV9S-2 skos:prefLabel "ATP Binding Cassette Transporter, Subfamily B"@en, "Sous-famille B de transporteurs à cassette liant l'ATP"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-JVCPPN5G-K . jvr:-ZX5LF3BD-1 skos:prefLabel "Drug Resistance, Multiple"@en, "Multirésistance aux médicaments"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-JVCPPN5G-K . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .