@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-JPNSL7G2-B mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-CJXMKG5Q-F, jvr:-G30ZJ446-J, jvr:-T2TS0S41-N, jvr:-THHNVC7V-3, jvr:-D0F21513-5, jvr:-M63HSDM7-1, jvr:-Q3979798-W, jvr:-FWD2BGQ0-9, jvr:-G7KXQWSR-5, jvr:-WZF2ZR3L-B, jvr:-L6C0XPHT-4, jvr:-NFTHND7Q-8, jvr:-H7K65Q8S-Z, jvr:-BT300B3G-Q, jvr:-SBNWSM1T-R, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-N2WP45CN-V, jvr:-NKM836P1-M, jvr:-WK5F724J-1, jvr:-TJHVZCRZ-0, jvr:-HQRFT0C6-B, jvr:-NHL3D2X0-S, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-NB0XHT3S-N ; skos:broader jvr:-Z5PBDGXG-S, jvr:-ZJXXGZ1B-L ; dc:modified "2016-05-27"^^xsd:date ; skos:altLabel "Ethylresorufin O-Deethylase"@en, "7-Ethoxyresorufin O-Deethylase"@en, "CYP 1A1"@fr, "CYP 1A1"@en, "CYP1A1"@fr, "CYP1A1"@en, "Éthoxyrésorufine-O-dééthylase"@fr, "EROD"@en, "EROD"@fr, "Ethoxyresorufin Dealkylase"@en, "Cytochrome P450 1A1"@fr, "CYP1A1 Protein"@en, "Ethoxyresorufin O-Deethylase"@en, "Cytochrome P450 IA1"@en ; skos:definition "A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity."@en ; skos:inScheme jvr: ; a skos:Concept, mesh:Descriptor ; dc:created "1996-06-24"^^xsd:date ; skos:prefLabel "Cytochrome P-450 CYP1A1"@fr, "Cytochrome P-450 CYP1A1"@en ; owl:sameAs ; skos:hiddenLabel "EC 1.14.14.1"@fr, "EC 1.14.14.1"@en ; mesh:registryNumber "EC 1.14.14.1" ; dc:established "1997-01-01"^^xsd:date . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZJXXGZ1B-L skos:prefLabel "Aryl Hydrocarbon Hydroxylases"@en, "Aryl hydrocarbon hydroxylases"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-JPNSL7G2-B . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z5PBDGXG-S skos:prefLabel "Cytochrome P450 Family 1"@en, "Famille-1 de cytochromes P450"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-JPNSL7G2-B . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .