@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJZB0TNF-8
  skos:prefLabel "17-Cétostéroïdes"@fr, "17-Ketosteroids"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-JM4JKTJ0-W .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-VSF4FK40-S
  skos:prefLabel "Congénères de l'oestradiol"@fr, "Estradiol Congeners"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-JM4JKTJ0-W .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NG0DT56C-P
  skos:prefLabel "Oestrogènes"@fr, "Estrogens"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-JM4JKTJ0-W
  mesh:allowableQualifier jvr:-R3QWLHRG-V, jvr:-D0F21513-5, jvr:-T9HQD7ST-J, jvr:-XV06LPML-W, jvr:-CJXMKG5Q-F, jvr:-Z9TSGBXH-4, jvr:-NB0XHT3S-N, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-G4R176S9-J, jvr:-G30ZJ446-J, jvr:-R0ZCQ8X6-J, jvr:-NFTHND7Q-8, jvr:-L6C0XPHT-4, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-G7KXQWSR-5, jvr:-WZF2ZR3L-B, jvr:-FWD2BGQ0-9, jvr:-THHNVC7V-3, jvr:-NHL3D2X0-S, jvr:-Q3979798-W, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-H7K65Q8S-Z ;
  skos:hiddenLabel "Estrone, (9 beta)-Isomer"@en, "Estrone, (8 alpha)-Isomer"@en, "Wehgen"@en, "Estrovarin"@en, "Estrone, (+-)-Isomer"@en, "Unigen"@en, "Folliculine"@fr, "Folliculin (Hormone)"@en, "Kestrone"@en ;
  dc:established "1966-01-01"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-TJZB0TNF-8, jvr:-HSF7KW88-K, jvr:-VSF4FK40-S ;
  skos:altLabel "2DI9HA706A"@fr, "2DI9HA706A"@en, "4680-83-5 ((+-)-isomer)"@fr, "4680-83-5 ((+-)-isomer)"@en, "Estra-1,3,5(10)-trien-17-one, 3-hydroxy-"@fr, "Estra-1,3,5(10)-trien-17-one, 3-hydroxy-"@en, "Estrone"@fr, "1225-03-2 ((9 beta)-isomer)"@fr, "1225-03-2 ((9 beta)-isomer)"@en, "53-16-7 (Estrone)"@fr, "53-16-7 (Estrone)"@en, "517-06-6 ((8 alpha)-isomer)"@fr, "517-06-6 ((8 alpha)-isomer)"@en ;
  dc:modified "2021-06-30"^^xsd:date ;
  dc:created "1999-01-01"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-NG0DT56C-P ;
  skos:inScheme jvr: ;
  skos:narrower jvr:-MDV2SZ6T-5 ;
  skos:definition "An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women."@en ;
  skos:prefLabel "Estrone"@en, "Oestrone"@fr ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D004970> .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HSF7KW88-K
  skos:prefLabel "Estrenes"@en, "Oestrènes"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-JM4JKTJ0-W .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MDV2SZ6T-5
  skos:prefLabel "Hydroxyoestrones"@fr, "Hydroxyestrones"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-JM4JKTJ0-W .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .