@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-ZN52ZLS2-M skos:prefLabel "Sirtuins"@en, "Sirtuines"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-K928J3KP-8 skos:prefLabel "Cholera Toxin"@en, "Toxine cholérique"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-DG4CNMBH-N skos:prefLabel "Toxine pertussique"@fr, "Pertussis Toxin"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S51BXXT9-2 skos:prefLabel "ADP-Ribosylation"@fr, "ADP-Ribosylation"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-J72RJJQG-0 . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NJNDKJX2-F skos:prefLabel "Poly(ADP-ribose) polymerases"@fr, "Poly(ADP-ribose) Polymerases"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-J72RJJQG-0 mesh:allowableQualifier jvr:-BT300B3G-Q, jvr:-M63HSDM7-1, jvr:-HQRFT0C6-B, jvr:-D0F21513-5, jvr:-TJHVZCRZ-0, jvr:-Q3979798-W, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-WK5F724J-1, jvr:-FWD2BGQ0-9, jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-W6SQV79N-S, jvr:-WZF2ZR3L-B, jvr:-NB0XHT3S-N, jvr:-SBNWSM1T-R, jvr:-CJXMKG5Q-F, jvr:-THHNVC7V-3, jvr:-N2WP45CN-V, jvr:-L6C0XPHT-4, jvr:-G30ZJ446-J, jvr:-G7KXQWSR-5, jvr:-T2TS0S41-N, jvr:-NHL3D2X0-S, jvr:-R3QWLHRG-V, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8, jvr:-T9HQD7ST-J ; skos:altLabel "ADP-Ribosyltransferase"@en, "81457-93-4 (CAS RN)"@fr, "81457-93-4 (CAS RN)"@en, "ART Transferase"@en, "ADP Ribose Transferase"@en, "ADP ribosyltransférases"@fr, "ART Transferases"@en, "ARTases"@en, "ARTase"@en, "ADPRTs"@en, "ADPRT"@en ; skos:hiddenLabel "Mono(ADP-Ribose) Transferase"@en, "EC 2.4.2.-"@fr, "EC 2.4.2.-"@en, "NAD+ ADP-Ribosyltransferase"@en, "NADP-ADPRTase"@en, "NAD ADP-Ribosyltransferase"@en, "Mono(ADPribosyl)transferase"@en, "Mono(ADP-Ribose) Transferases"@en, "MonoADPribosyltransferase"@en, "NAD-Agmatine ADP-Ribosyltransferase"@en, "Mono ADPribose Transferase"@en, "EC 2.4.2.31"@fr, "EC 2.4.2.31"@en, "Mono(ADP-Ribosyl)transferase"@en, "NAD-Arginine ADP-Ribosyltransferase"@en, "NAD(+)-L-arginine ADP-D-ribosyltransferase"@en, "Mono ADPribose Transferases"@en, "NADP-Arginine ADP-Ribosyltransferase"@en, "NAD(P)(+)-Arginine ADP-Ribosyltransferase"@en, "Mono-ADP-Ribosyltransferase"@en, "Mono ADP-ribose Transferases"@en ; skos:broader jvr:-NHZX9FSC-X ; skos:prefLabel "ADP ribose transferases"@fr, "ADP Ribose Transferases"@en ; skos:narrower jvr:-K928J3KP-8, jvr:-KWJMKS1Z-3, jvr:-ZN52ZLS2-M, jvr:-NJNDKJX2-F, jvr:-L2H7HJQN-B, jvr:-DG4CNMBH-N ; dc:created "2002-07-02"^^xsd:date ; dc:established "2003-01-01"^^xsd:date ; a skos:Concept, mesh:Descriptor ; skos:related jvr:-S51BXXT9-2 ; dc:modified "2017-04-14"^^xsd:date ; owl:sameAs ; mesh:registryNumber "EC 2.4.2.-", "EC 2.4.2.31" ; skos:definition "Enzymes that transfer the ADP-RIBOSE group of NAD or NADP to proteins or other small molecules. Transfer of ADP-ribose to water (i.e., hydrolysis) is catalyzed by the NADASES. The mono(ADP-ribose)transferases transfer a single ADP-ribose. POLY(ADP-RIBOSE) POLYMERASES transfer multiple units of ADP-ribose to protein targets, building POLY ADENOSINE DIPHOSPHATE RIBOSE in linear or branched chains. Enzymes that catalyze the transfer of one ADP-ribose moiety from NAD+ to an amino acid residue in specific protein substrates. This reaction is catalyzed by prokaryotic and eukaryotic enzymes. Mono-ADP-ribosylation is a mechanism of action common to several bacterial toxins. An enzyme that catalyzes the transfer of the ADP-ribose moiety from NAD+ or NADP+ to specific protein substrates with arginine, arginine-type compounds, agmatine, or guanidine as acceptors. This mono-ADP-ribosylation reaction is the mechanism of action common to several bacterial toxins affecting profound changes in cellular metabolism, such as activation of adenylate cyclase, regulation of protein synthesis at the level of elongation factor 2, and ion transport across biological membranes. An enzyme that catalyze the transfer of ADP-RIBOSE from NAD+ to an amino acid residue in a specific protein substrate. This reaction is catalyzed by both mono(ADP-ribose) transferases as well as POLY(ADP-RIBOSE) POLYMERASES. When the term NAD+ ADP-Ribosyltransferase refers to EC 2.4.2.30 it is referring to POLY(ADP-RIBOSE) POLYMERASES."@en ; skos:inScheme jvr: . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KWJMKS1Z-3 skos:prefLabel "Diphtheria Toxin"@en, "Toxine diphtérique"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NHZX9FSC-X skos:prefLabel "Pentosyltransferases"@fr, "Pentosyltransferases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-J72RJJQG-0 . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L2H7HJQN-B skos:prefLabel "NAD+ Nucleosidase"@en, "NAD nucleosidase"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-J72RJJQG-0 .