@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-RBB5D30Q-K skos:prefLabel "Cytotoxicité immunologique"@fr, "Cytotoxicity, Immunologic"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-J2XJX3ZP-7 . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RBRTJ68X-8 skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ; a mesh:Descriptor, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CMVCHB10-F skos:prefLabel "Protéines du système du complément"@fr, "Complement System Proteins"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-J2XJX3ZP-7 . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-J2XJX3ZP-7 mesh:allowableQualifier jvr:-BT300B3G-Q, jvr:-NB0XHT3S-N, jvr:-CJXMKG5Q-F, jvr:-THHNVC7V-3, jvr:-S0CS1X5R-5, jvr:-L6C0XPHT-4, jvr:-N2WP45CN-V, jvr:-W6SQV79N-S, jvr:-G30ZJ446-J, jvr:-NKM836P1-M, jvr:-R3QWLHRG-V, jvr:-G7KXQWSR-5, jvr:-T2TS0S41-N, jvr:-M63HSDM7-1, jvr:-Z9TSGBXH-4, jvr:-Q3979798-W, jvr:-WZF2ZR3L-B, jvr:-CB30NGKB-3, jvr:-XV06LPML-W, jvr:-HQRFT0C6-B, jvr:-SBNWSM1T-R, jvr:-T9HQD7ST-J, jvr:-NFTHND7Q-8, jvr:-WK5F724J-1, jvr:-TJHVZCRZ-0, jvr:-FWD2BGQ0-9, jvr:-D0F21513-5, jvr:-R0ZCQ8X6-J, jvr:-H7K65Q8S-Z ; skos:related jvr:-RBB5D30Q-K ; skos:altLabel "Terminal Complement Complex"@en, "Cytolytic Terminal Complement Complex"@en, "Complexe d'attaque membranaire"@fr, "Membrane Attack Complex"@en, "Complexe C5b-9"@fr, "C 5b-9"@en, "Complement Complex C5b-9"@en, "C5b-9"@en, "C5b-8-poly-C9"@en, "Complexe lytique terminal du complément"@fr ; skos:prefLabel "Complement Membrane Attack Complex"@en, "Complexe d'attaque membranaire du complément"@fr ; skos:inScheme jvr: ; dc:created "1989-05-25"^^xsd:date ; owl:sameAs ; a mesh:Descriptor, skos:Concept ; dc:modified "2005-06-30"^^xsd:date ; skos:definition "A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the \"membrane attack complex\" or MAC."@en ; mesh:pharmacologicalAction jvr:-RBRTJ68X-8 ; dc:established "1990-01-01"^^xsd:date ; skos:broader jvr:-CMVCHB10-F . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .