@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DPGGJ64L-N
  skos:prefLabel "Membrane Proteins"@en, "Protéines membranaires"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-HSM2M31L-2 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D9S3MC53-4
  skos:prefLabel "Guanylate kinase"@fr, "Guanylate Kinases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-HSM2M31L-2 .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HSM2M31L-2
  mesh:allowableQualifier jvr:-TJHVZCRZ-0, jvr:-THHNVC7V-3, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-R0ZCQ8X6-J, jvr:-NFTHND7Q-8, jvr:-WZF2ZR3L-B, jvr:-NHL3D2X0-S, jvr:-M63HSDM7-1, jvr:-L6C0XPHT-4, jvr:-R3QWLHRG-V, jvr:-FWD2BGQ0-9, jvr:-W6SQV79N-S, jvr:-SBNWSM1T-R, jvr:-Q3979798-W, jvr:-Z9TSGBXH-4, jvr:-WK5F724J-1, jvr:-XV06LPML-W, jvr:-CJXMKG5Q-F, jvr:-T9HQD7ST-J, jvr:-HQRFT0C6-B, jvr:-T2TS0S41-N, jvr:-G7KXQWSR-5, jvr:-D0F21513-5, jvr:-BT300B3G-Q, jvr:-NB0XHT3S-N, jvr:-H7K65Q8S-Z, jvr:-G30ZJ446-J, jvr:-N2WP45CN-V ;
  skos:altLabel "Homologue-1 de la protéine Disks Large"@fr, "Protéine 97 associée aux synapses"@fr, "Synapse-Associated Protein 97"@en ;
  skos:prefLabel "Discs Large Homolog 1 Protein"@en, "Homologue-1 de la protéine Discs Large"@fr ;
  dc:established "2018-01-01"^^xsd:date ;
  skos:inScheme jvr: ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-DPGGJ64L-N, jvr:-QL35BZGZ-C, jvr:-D9S3MC53-4 ;
  dc:created "2017-07-11"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000074288> ;
  dc:modified "2017-02-27"^^xsd:date ;
  skos:definition "A signaling adaptor protein that contains three PDZ DOMAINS; an SH3 DOMAIN; and a GUANYLATE KINASE-like C-terminal region. It has an essential role in animal development and recruits ion channels, receptors, and signaling molecules to discrete plasma membrane regions of polarized cells in the HEART ATRIA MYOCARDIUM. It functions in the assembly of ADHERENS JUNCTIONS and regulation of CELL PROLIFERATION; synaptogenesis, LYMPHOCYTE ACTIVATION; and controls expression of KV4 POTASSIUM CHANNELS to regulate excitability of CARDIAC MYOCYTES."@en .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QL35BZGZ-C
  skos:prefLabel "Adaptor Proteins, Signal Transducing"@en, "Protéines adaptatrices de la transduction du signal"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-HSM2M31L-2 .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .