@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HC1BZM84-7
  skos:prefLabel "Immunogenetic Phenomena"@en, "Phénomènes immunogénétiques"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-HCMGCMNM-C .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HCMGCMNM-C
  mesh:allowableQualifier jvr:-H7K65Q8S-Z, jvr:-WZF2ZR3L-B, jvr:-S0CS1X5R-5, jvr:-Z9TSGBXH-4, jvr:-N2WP45CN-V ;
  skos:broader jvr:-HC1BZM84-7, jvr:-B5CT14VJ-D ;
  a mesh:Descriptor, skos:Concept ;
  skos:prefLabel "Antibody Diversity"@en, "Diversité des anticorps"@fr ;
  dc:established "1980-01-01"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000916> ;
  skos:definition "The phenomenon of immense variability characteristic of ANTIBODIES. It enables the IMMUNE SYSTEM to react specifically against the essentially unlimited kinds of ANTIGENS it encounters. Antibody diversity is accounted for by three main theories: (1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; (2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and (3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of IMMUNOGLOBULIN VARIABLE REGION gene segments during the differentiation of the ANTIBODY-PRODUCING CELLS."@en ;
  skos:related jvr:-R24GHKXD-S ;
  dc:modified "2015-06-22"^^xsd:date ;
  skos:hiddenLabel "Théorie de la lignée germinale"@fr, "Germ Line Theory"@en ;
  dc:created "1979-02-23"^^xsd:date ;
  skos:inScheme jvr: .

jvr:-B5CT14VJ-D
  skos:prefLabel "Genetic Variation"@en, "Variation génétique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-HCMGCMNM-C .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-R24GHKXD-S
  skos:prefLabel "Gene Rearrangement"@en, "Réarrangement des gènes"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-HCMGCMNM-C .

