@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZL2HV2BR-K
  skos:prefLabel "Receptors, Antigen, B-Cell"@en, "Récepteurs pour l'antigène des lymphocytes B"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-H4Q8LTGW-H .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-DM2WTP37-D
  skos:prefLabel "Immunoglobulin Light Chains, Surrogate"@en, "Pseudochaines légères des immunoglobulines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-H4Q8LTGW-H .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H4Q8LTGW-H
  mesh:allowableQualifier jvr:-H7K65Q8S-Z, jvr:-M63HSDM7-1, jvr:-NHL3D2X0-S, jvr:-CJXMKG5Q-F, jvr:-N2WP45CN-V, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-HQRFT0C6-B, jvr:-T2TS0S41-N, jvr:-R0ZCQ8X6-J, jvr:-FWD2BGQ0-9, jvr:-S0CS1X5R-5, jvr:-W6SQV79N-S, jvr:-WZF2ZR3L-B, jvr:-Q3979798-W, jvr:-G7KXQWSR-5, jvr:-SBNWSM1T-R, jvr:-L6C0XPHT-4, jvr:-TJHVZCRZ-0 ;
  skos:broader jvr:-ZL2HV2BR-K ;
  skos:narrower jvr:-DM2WTP37-D ;
  skos:altLabel "Récepteurs des précurseurs des lymphocytes B"@fr, "Récepteurs des cellules pré-B"@fr, "Pre-B Cell Receptor"@en, "Récepteurs des précurseurs des cellules B"@fr, "préBCR"@fr, "pré-BCR"@fr ;
  skos:inScheme jvr: ;
  skos:prefLabel "Récepteurs des lymphocytes pré-B"@fr, "Pre-B Cell Receptors"@en ;
  skos:definition "Membrane proteins in precursor B-LYMPHOCYTES (pre-B Cells). They are composed of membrane-bound MU IMMUNOGLOBULIN HEAVY CHAINS in complex with SURROGATE LIGHT CHAINS instead of conventional IMMUNOGLOBULIN LIGHT CHAINS. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the pre-B cell receptors is an important checkpoint in the development of mature B cells."@en ;
  dc:established "2008-01-01"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D054420> ;
  a mesh:Descriptor, skos:Concept ;
  dc:created "2007-07-09"^^xsd:date ;
  dc:modified "2017-06-30"^^xsd:date .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .