@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-H4P82Q0B-B skos:hiddenLabel "ADN ligase IV"@fr, "DNA Ligase II"@en, "DNA Ligase IIIalpha"@en, "ADN ligase II"@fr, "LIGIIIalpha Protein"@en, "ADN ligase III"@fr, "DNA Ligase III"@en, "DNA ligase I"@fr, "DNA ligase IV"@fr, "DNA ligase III"@fr, "DNA ligase II"@fr, "DNA Ligase IV"@en, "ADN ligase I"@fr, "EC 6.5.1.1"@fr, "EC 6.5.1.1"@en, "DNA Ligase I"@en ; mesh:allowableQualifier jvr:-WK5F724J-1, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-THHNVC7V-3, jvr:-NB0XHT3S-N, jvr:-TJHVZCRZ-0, jvr:-BT300B3G-Q, jvr:-D0F21513-5, jvr:-SBNWSM1T-R, jvr:-WZF2ZR3L-B, jvr:-CJXMKG5Q-F, jvr:-Q3979798-W, jvr:-XV06LPML-W, jvr:-CB30NGKB-3, jvr:-M63HSDM7-1, jvr:-Z9TSGBXH-4, jvr:-S0CS1X5R-5, jvr:-FWD2BGQ0-9, jvr:-H7K65Q8S-Z, jvr:-N2WP45CN-V, jvr:-NFTHND7Q-8, jvr:-G7KXQWSR-5, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-NHL3D2X0-S, jvr:-T9HQD7ST-J, jvr:-NKM836P1-M, jvr:-T2TS0S41-N, jvr:-R3QWLHRG-V ; owl:sameAs ; a skos:Concept, mesh:Descriptor ; dc:created "2016-07-08"^^xsd:date ; skos:altLabel "DNA Ligases, ATP-Dependent"@en, "ADN ligase à ATP"@fr, "Polydeoxyribonucleotide Synthase ATP"@en, "ATP-Dependent DNA Ligase"@en ; mesh:registryNumber "EC 6.5.1.1" ; skos:inScheme jvr: ; skos:broader jvr:-SLXP0SW1-Z ; skos:prefLabel "DNA Ligase ATP"@en, "DNA ligase ATP"@fr ; dc:modified "2021-06-30"^^xsd:date ; dc:established "2017-01-01"^^xsd:date ; skos:definition "ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent."@en . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-SLXP0SW1-Z skos:prefLabel "DNA Ligases"@en, "DNA ligases"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-H4P82Q0B-B . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .