@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-JQCG9VKP-7
  skos:prefLabel "Modulateurs du transport transmembranaire"@fr, "Membrane Transport Modulators"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-GZ0L4XMG-7 .

jvr:-J6NZHJKG-6 mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-GZ0L4XMG-7
  dc:created "2005-06-30"^^xsd:date ;
  skos:altLabel "Thiazide Sensitive NaCl Cotransporter Inhibitor"@en, "Inhibiteurs du co-transporteur Na-Cl"@fr, "Inhibiteurs du cotransport NaCl sensible aux thiazides"@fr, "Inhibiteurs du co-transport chlorure sodium"@fr, "Inhibiteurs du cotransport chlorure sodium"@fr, "Inhibiteurs du symporteur Na-Cl"@fr, "Inhibiteurs du cotransport Na-Cl sensible aux thiazides"@fr, "Sodium Chloride Cotransporter Inhibitor"@en, "Inhibiteurs du cotransport de type symport Cl-/Na+"@fr, "Inhibiteurs du cotransporteur Na-Cl"@fr, "Inhibiteurs des symporteurs des ions chlorure et sodium"@fr, "Inhibiteurs du symport de chlorure sodium"@fr, "Thiazide Sensitive NaCl Cotransporter Inhibitors"@en, "Inhibiteurs du co-transport de chlorure de sodium"@fr, "Sodium Chloride Symporter Inhibitor"@en, "Inhibiteurs du cotransport de chlorure de sodium"@fr, "Sodium Chloride Cotransporter Inhibitors"@en ;
  mesh:allowableQualifier jvr:-NB0XHT3S-N, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-Q3979798-W, jvr:-NHL3D2X0-S, jvr:-WK5F724J-1, jvr:-CB30NGKB-3, jvr:-TJHVZCRZ-0, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-SBNWSM1T-R, jvr:-NFTHND7Q-8, jvr:-W6SQV79N-S, jvr:-G30ZJ446-J, jvr:-D0F21513-5, jvr:-FWD2BGQ0-9, jvr:-H7K65Q8S-Z, jvr:-NKM836P1-M, jvr:-T9HQD7ST-J, jvr:-S0CS1X5R-5, jvr:-L6C0XPHT-4, jvr:-THHNVC7V-3 ;
  dc:modified "2021-06-30"^^xsd:date ;
  skos:hiddenLabel "Potassium Depleting Diuretic"@en, "Diurétiques thiazides"@fr, "Thiazide Diuretic"@en, "Diurétiques hypokaliémiants"@fr, "Diuretics, Thiazide"@en, "Benzothiadiazine Diuretics"@en, "Benzothiadiazides"@fr, "Diurétiques thiaziques"@fr, "Benzothiadiazine Diuretic"@en, "Thiazide Diuretics"@en, "Potassium Depleting Diuretics"@en, "Diurétiques thiazidiques"@fr ;
  dc:established "2006-01-01"^^xsd:date ;
  skos:broader jvr:-JQCG9VKP-7, jvr:-RZWRW1JM-Z ;
  skos:inScheme jvr: ;
  skos:prefLabel "Sodium Chloride Symporter Inhibitors"@en, "Inhibiteurs du symport chlorure sodium"@fr ;
  skos:definition "Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. Diuretics characterized as analogs of 1,2,4-benzothiadiazine-1,1-dioxide. All have a common mechanism of action and differ primarily in the dose required to produce a given effect. They act directly on the kidney to increase the excretion of sodium chloride and water. Also, diuretics increase excretion of potassium ions."@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D049993> ;
  a mesh:Descriptor, skos:Concept .

jvr:-QLJPRJFD-L mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-J1GG5JLW-9 mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MKBXNXN1-C mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RZWRW1JM-Z
  skos:prefLabel "Diurétiques"@fr, "Diuretics"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-GZ0L4XMG-7 .

jvr:-RKXHBG4B-R mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-ZC8FLNGW-P mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MZDDP60B-Q mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-J3QT9JR9-Q mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-DKTC8SHJ-D mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T40FKJTD-W mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .
jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-K5JBXNX3-T mesh:pharmacologicalAction jvr:-GZ0L4XMG-7 .