@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-SGRTB03P-B skos:prefLabel "Antiphospholipid Syndrome"@en, "Syndrome des anticorps antiphospholipides"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-GKHRD82S-M . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T41MSMDT-0 skos:prefLabel "Blood Coagulation Factor Inhibitors"@en, "Inhibiteurs des facteurs de la coagulation sanguine"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-GKHRD82S-M . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RBRTJ68X-8 skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ; a mesh:Descriptor, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-GKHRD82S-M mesh:allowableQualifier jvr:-NB0XHT3S-N, jvr:-G7KXQWSR-5, jvr:-HQRFT0C6-B, jvr:-WZF2ZR3L-B, jvr:-N2WP45CN-V, jvr:-T2TS0S41-N, jvr:-W6SQV79N-S, jvr:-CB30NGKB-3, jvr:-NKM836P1-M, jvr:-L6C0XPHT-4, jvr:-Q3979798-W, jvr:-Z9TSGBXH-4, jvr:-TJHVZCRZ-0, jvr:-D0F21513-5, jvr:-NFTHND7Q-8, jvr:-XV06LPML-W, jvr:-SBNWSM1T-R, jvr:-FWD2BGQ0-9, jvr:-S0CS1X5R-5, jvr:-H7K65Q8S-Z, jvr:-G30ZJ446-J, jvr:-BT300B3G-Q, jvr:-NHL3D2X0-S ; skos:altLabel "Lupus Anticoagulant"@en, "Anti-coagulant du lupus"@fr, "Inhibiteur lupique de la coagulation sanguine"@fr, "Coagulation Inhibitor, Lupus"@en, "Anti-coagulant lupique"@fr, "Inhibitor, Lupus Coagulation"@en, "Anticoagulant lupique"@fr, "Anticoagulant, Lupus"@en, "Anticoagulant du lupus"@fr ; skos:inScheme jvr: ; skos:related jvr:-SGRTB03P-B, jvr:-MZMS174K-P ; skos:definition "An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications."@en ; skos:prefLabel "Inhibiteur lupique de la coagulation"@fr, "Lupus Coagulation Inhibitor"@en ; a skos:Concept, mesh:Descriptor ; skos:broader jvr:-H445G5XT-C, jvr:-T41MSMDT-0 ; mesh:pharmacologicalAction jvr:-RBRTJ68X-8 ; dc:created "1991-07-12"^^xsd:date ; dc:established "1992-01-01"^^xsd:date ; dc:modified "2005-07-19"^^xsd:date ; owl:sameAs . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H445G5XT-C skos:prefLabel "Antibodies, Antiphospholipid"@en, "Anticorps antiphospholipides"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-GKHRD82S-M . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-MZMS174K-P skos:prefLabel "Lupus érythémateux disséminé"@fr, "Lupus Erythematosus, Systemic"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-GKHRD82S-M .