@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FNVPFQ7G-3
  skos:hiddenLabel "ARCH Age-related Clonal Hematopoiesis"@en, "Hématopoïèse clonale de potentiel indéterminé"@fr, "CHIP Clonal Hematopoiesis of Indeterminate Potential"@en, "Cytopénie clonale de signification indéterminée (CCUS)"@fr, "Hématopoïèse clonale de signification indéterminée"@fr, "Cytopénie clonale de signification indéterminée"@fr, "Cytopénie idiopathique de signification indéterminée"@fr, "Clonal Hematopoiesis of Indeterminate Potential"@en, "Clonal Cytopenia of Undetermined Significance"@en, "Age-related Clonal Hematopoiesis"@en, "Hématopoïèse clonale liée à l'âge (ARCH)"@fr, "Hématopoïèse clonale liée à l'âge"@fr, "CCUS Clonal Cytopenia of Undetermined Significance"@en, "Cytopénie idiopathique de signification indéterminée (ICUS)"@fr, "Idiopathic Cytopenias of Undetermined Significance"@en, "Hématopoïèse clonale de potentiel indéterminé (CHIP)"@fr, "ICUS Idiopathic Cytopenias of Undetermined Significance"@en ;
  mesh:allowableQualifier jvr:-H7K65Q8S-Z, jvr:-WZF2ZR3L-B, jvr:-N2WP45CN-V, jvr:-Z9TSGBXH-4, jvr:-S0CS1X5R-5 ;
  skos:definition "Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases. When variant allele fraction is at least 2% and is present in the absence of severe cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP)."@en ;
  skos:prefLabel "Hématopoïèse clonale"@fr, "Clonal Hematopoiesis"@en ;
  skos:inScheme jvr: ;
  skos:broader jvr:-MSFX5X3Q-8, jvr:-BM9JSBTD-N ;
  dc:created "2020-07-07"^^xsd:date ;
  dc:modified "2020-05-27"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000082182> ;
  dc:established "2021-01-01"^^xsd:date .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BM9JSBTD-N
  skos:prefLabel "Évolution clonale"@fr, "Clonal Evolution"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-FNVPFQ7G-3 .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MSFX5X3Q-8
  skos:prefLabel "Hematopoiesis"@en, "Hématopoïèse"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-FNVPFQ7G-3 .

jvr: a skos:ConceptScheme .