@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-JQCG9VKP-7
  skos:prefLabel "Modulateurs du transport transmembranaire"@fr, "Membrane Transport Modulators"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-FHKR4BBJ-G .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-B3S97GKG-S mesh:pharmacologicalAction jvr:-FHKR4BBJ-G .
jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-KMKMT884-R
  skos:prefLabel "Calcium-Regulating Hormones and Agents"@en, "Hormones et agents régulant le calcium"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-FHKR4BBJ-G .

jvr:-FHKR4BBJ-G
  skos:altLabel "Agonistes des canaux du calcium"@fr, "Activateurs des canaux du calcium"@fr, "Activateurs des canaux calciques"@fr, "Calcium Channel Agonist"@en, "Calcium Channel Activators"@en ;
  mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-H7K65Q8S-Z, jvr:-R3QWLHRG-V, jvr:-FWD2BGQ0-9, jvr:-L6C0XPHT-4, jvr:-T9HQD7ST-J, jvr:-CB30NGKB-3, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-D0F21513-5, jvr:-BT300B3G-Q, jvr:-NB0XHT3S-N, jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-G30ZJ446-J, jvr:-XV06LPML-W, jvr:-S0CS1X5R-5, jvr:-THHNVC7V-3, jvr:-NFTHND7Q-8, jvr:-NHL3D2X0-S, jvr:-NKM836P1-M, jvr:-HQRFT0C6-B ;
  skos:prefLabel "Agonistes des canaux calciques"@fr, "Calcium Channel Agonists"@en ;
  dc:established "1988-01-01"^^xsd:date ;
  dc:created "1987-03-23"^^xsd:date ;
  skos:hiddenLabel "Exogenous Calcium Channel Agonists"@en, "Calcium Channel Agonists, Exogenous"@en, "Agonistes exogènes des canaux calciques"@fr, "Activateurs exogènes des canaux calciques"@fr ;
  skos:related jvr:-QS45FLXS-3 ;
  skos:broader jvr:-KMKMT884-R, jvr:-R9SB4WRS-X, jvr:-JQCG9VKP-7 ;
  skos:definition "Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture."@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:inScheme jvr: ;
  dc:modified "2018-05-22"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D002120> .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R9SB4WRS-X
  skos:prefLabel "Vasoconstricteurs"@fr, "Vasoconstrictor Agents"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-FHKR4BBJ-G .

jvr:-F69J928B-9 mesh:pharmacologicalAction jvr:-FHKR4BBJ-G .
jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QS45FLXS-3
  skos:prefLabel "Canaux calciques"@fr, "Calcium Channels"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-FHKR4BBJ-G .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .