@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-CL96NQQZ-V skos:prefLabel "GABA Agents"@en, "Agents GABA"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-DW8H3MNZ-P . jvr:-QQZD4RRS-Q mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KW26S3M1-N skos:prefLabel "Anxiolytiques"@fr, "Anti-Anxiety Agents"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-DW8H3MNZ-P . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-HLMF1K1M-6 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-RPRSD0TF-Z mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L4D1QCGV-8 skos:prefLabel "Hypnotics and Sedatives"@en, "Hypnotiques et sédatifs"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-DW8H3MNZ-P . jvr:-DW8H3MNZ-P mesh:allowableQualifier jvr:-D0F21513-5, jvr:-NKM836P1-M, jvr:-HQRFT0C6-B, jvr:-G30ZJ446-J, jvr:-THHNVC7V-3, jvr:-WK5F724J-1, jvr:-TJHVZCRZ-0, jvr:-NB0XHT3S-N, jvr:-T9HQD7ST-J, jvr:-BT300B3G-Q, jvr:-R3QWLHRG-V, jvr:-SBNWSM1T-R, jvr:-FWD2BGQ0-9, jvr:-W6SQV79N-S, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8, jvr:-R0ZCQ8X6-J, jvr:-XV06LPML-W, jvr:-CB30NGKB-3, jvr:-H7K65Q8S-Z, jvr:-M63HSDM7-1, jvr:-NHL3D2X0-S, jvr:-L6C0XPHT-4, jvr:-Q3979798-W ; skos:related jvr:-L4D1QCGV-8, jvr:-DKKTQGP7-S, jvr:-BZ9H76ZK-T, jvr:-KW26S3M1-N ; a skos:Concept, mesh:Descriptor ; dc:modified "2005-06-30"^^xsd:date ; skos:prefLabel "Modulateurs GABA"@fr, "GABA Modulators"@en ; skos:altLabel "gamma-Aminobutyric Acid Modulators"@en, "Modulateurs de l'acide amino-4 butyrique"@fr, "Modulateurs GABAergiques"@fr, "GABAergic Modulators"@en ; skos:definition "Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here."@en ; dc:created "1994-06-03"^^xsd:date ; owl:sameAs ; skos:broader jvr:-CL96NQQZ-V ; dc:established "1995-01-01"^^xsd:date ; skos:inScheme jvr: . jvr:-M9VM6G0L-Z mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-SRZ1R0DN-B mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-HC5CJKWG-9 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W61LQSV0-B mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-X1QKR4FR-8 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr: a skos:ConceptScheme . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-DKKTQGP7-S skos:prefLabel "Transporteurs de GABA"@fr, "GABA Plasma Membrane Transport Proteins"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-DW8H3MNZ-P . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TZNDGJ4G-K mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-KFM9MV7D-Q mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-T5H1W68G-3 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-VL46S3L4-4 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-L2BRZ140-R mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L0G1NHNH-4 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-PF0N3ZXQ-X mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-RC2325F9-V mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-QRV7W9W2-X mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-WRC0D41G-9 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-X6QJ9L5M-0 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-NDBC1KBX-9 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-BZ9H76ZK-T skos:prefLabel "Anesthetics, General"@en, "Anesthésiques généraux"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-DW8H3MNZ-P . jvr:-G7RKQRLK-H mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-LWJ89GHH-V mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-PF58HR0N-K mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-V6GTKN9B-L mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-T16S7VRS-T mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-XRNGF8QX-P mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-B8W0MMSV-2 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-C2NMBH2M-7 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-V3ZD0CKH-Q mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-K1W2MB1W-6 mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-L375H2BH-D mesh:pharmacologicalAction jvr:-DW8H3MNZ-P . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .