@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-N47B1N52-T
  skos:prefLabel "Équivalence thérapeutique"@fr, "Therapeutic Equivalency"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-VK6W2RP6-M
  skos:prefLabel "Distribution tissulaire"@fr, "Tissue Distribution"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-GS2XGVWP-F
  skos:prefLabel "Metabolic Clearance Rate"@en, "Taux de clairance métabolique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-Q4XJ96SF-P
  skos:prefLabel "Chronopharmacokinetics"@en, "Chronopharmacocinétique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-Z2RBPV8L-3
  skos:prefLabel "Voies d'élimination des médicaments"@fr, "Drug Elimination Routes"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-VGBMKR2G-Z
  skos:prefLabel "Biodisponibilité"@fr, "Biological Availability"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-MBXKQRFT-B
  skos:prefLabel "Biotransformation"@en, "Biotransformation"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-LWWT65FB-4
  skos:prefLabel "Métabolisme"@fr, "Metabolism"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-D26CQDP7-F .

jvr:-GC2TCGZS-J
  skos:prefLabel "Area Under Curve"@en, "Aire sous la courbe"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr: a skos:ConceptScheme .
jvr:-HSBLRH61-0
  skos:prefLabel "Phénomènes pharmacologiques et toxicologiques"@fr, "Pharmacological and Toxicological Phenomena"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-D26CQDP7-F .

jvr:-D26CQDP7-F
  skos:hiddenLabel "LADMER"@en, "ADMET"@en, "Liberation, Absorption, Distribution, Metabolism, Elimination, and Response"@en, "Absorption, Distribution, Metabolism, and Elimination"@en, "ADME"@en, "ADME-Tox"@en, "Absorption, Distribution, Metabolism, Elimination, and Toxicology"@en ;
  skos:broader jvr:-LWWT65FB-4, jvr:-HSBLRH61-0 ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D010599> ;
  dc:modified "2020-07-22"^^xsd:date ;
  skos:narrower jvr:-VGBMKR2G-Z, jvr:-Z2RBPV8L-3, jvr:-N47B1N52-T, jvr:-VK6W2RP6-M, jvr:-GC2TCGZS-J, jvr:-C9MK6FH4-9, jvr:-Q4XJ96SF-P, jvr:-MVLFKQTL-R, jvr:-GS2XGVWP-F, jvr:-MBXKQRFT-B ;
  dc:created "1987-04-18"^^xsd:date ;
  skos:prefLabel "Pharmacocinétique"@fr, "Pharmacokinetics"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:altLabel "Kinetics, Drug"@en, "Cinétique des médicaments"@fr, "Drug Kinetics"@en ;
  dc:established "1988-01-01"^^xsd:date ;
  skos:definition "Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology."@en ;
  skos:inScheme jvr: .

jvr:-C9MK6FH4-9
  skos:prefLabel "Libération de médicament"@fr, "Drug Liberation"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .

jvr:-MVLFKQTL-R
  skos:prefLabel "Absorption"@en, "Absorption"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-D26CQDP7-F .