@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-CQQB7N39-M
  skos:altLabel "O3FX965V0I"@fr, "O3FX965V0I"@en, "Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-"@fr, "Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-"@en, "1424-27-7 (mono-Na salt)"@fr, "1424-27-7 (mono-Na salt)"@en, "59-66-5 (Acetazolamide)"@fr, "59-66-5 (Acetazolamide)"@en ;
  skos:hiddenLabel "Acétazolamide de sodium"@fr, "Huma-Zolamide"@en, "Acétazolamide sodique"@fr, "Apo-Acetazolamide"@en, "Diacarb"@en, "Acetazolamide, Monosodium Salt"@en, "Edemox"@en, "Défiltran"@en, "Glauconox"@en, "Acétazolamide de monosodium"@fr, "Acetazolam"@en, "Diamox"@en, "Acetadiazol"@en, "Ak-Zol"@en, "Diuramide"@en, "Acetazolamide Sodium, (Sterile)"@en, "Acétazolamide monosodique"@fr, "Glaupax"@en ;
  mesh:allowableQualifier jvr:-NFTHND7Q-8, jvr:-THHNVC7V-3, jvr:-BT300B3G-Q, jvr:-CB30NGKB-3, jvr:-FWD2BGQ0-9, jvr:-NHL3D2X0-S, jvr:-WK5F724J-1, jvr:-R0ZCQ8X6-J, jvr:-SBNWSM1T-R, jvr:-G4R176S9-J, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-T9HQD7ST-J, jvr:-NKM836P1-M, jvr:-Q3979798-W, jvr:-NB0XHT3S-N, jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-M63HSDM7-1, jvr:-S0CS1X5R-5, jvr:-XV06LPML-W, jvr:-R3QWLHRG-V, jvr:-D0F21513-5 ;
  mesh:pharmacologicalAction jvr:-RZWRW1JM-Z, jvr:-NLDQFD28-5, jvr:-SLLN8F4V-8 ;
  skos:broader jvr:-K0XHWGGT-L ;
  dc:created "1999-01-01"^^xsd:date ;
  dc:modified "2016-06-24"^^xsd:date ;
  skos:prefLabel "Acétazolamide"@fr, "Acetazolamide"@en ;
  skos:definition "One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)"@en ;
  a skos:Concept, mesh:Descriptor ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000086> ;
  skos:inScheme jvr: ;
  dc:established "1966-01-01"^^xsd:date .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-SLLN8F4V-8
  skos:prefLabel "Anticonvulsants"@en, "Anticonvulsivants"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RZWRW1JM-Z
  skos:prefLabel "Diurétiques"@fr, "Diuretics"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-K0XHWGGT-L
  skos:prefLabel "Thiadiazoles"@fr, "Thiadiazoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-CQQB7N39-M .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NLDQFD28-5
  skos:prefLabel "Inhibiteurs de l'anhydrase carbonique"@fr, "Carbonic Anhydrase Inhibitors"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .