@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-CGCP4DFF-R
  skos:narrower jvr:-B91PLTDL-F, jvr:-Z3D0THLS-4, jvr:-T5CCLCV4-2, jvr:-VVJ7SMDH-Q, jvr:-CSRVSGPJ-P, jvr:-JPRJH6XQ-G, jvr:-B89T56WP-1, jvr:-QW6NM13W-2, jvr:-QMN00FPR-M, jvr:-PR5B8C7D-F, jvr:-N5WPRGPS-F, jvr:-CCPRHMPB-4, jvr:-ZGM7ZWZH-Q, jvr:-BH3JH250-T, jvr:-DVHNWMLM-V, jvr:-Q6J78B97-Z, jvr:-DZJ47ZRM-V ;
  skos:altLabel "Hydroxylase"@en, "Monooxygenase"@en, "Mixed Function Oxidase"@en, "Mixed Function Oxygenase"@en, "Hydroxylases"@en, "Hydroxylases"@fr, "Mixed Function Oxidases"@en, "Monooxygenases"@fr, "Monooxygenases"@en ;
  mesh:allowableQualifier jvr:-CB30NGKB-3, jvr:-CJXMKG5Q-F, jvr:-BT300B3G-Q, jvr:-T9HQD7ST-J, jvr:-XV06LPML-W, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-R3QWLHRG-V, jvr:-NFTHND7Q-8, jvr:-Q3979798-W, jvr:-Z9TSGBXH-4, jvr:-N2WP45CN-V, jvr:-S0CS1X5R-5, jvr:-NKM836P1-M, jvr:-H7K65Q8S-Z, jvr:-THHNVC7V-3, jvr:-HQRFT0C6-B, jvr:-FWD2BGQ0-9, jvr:-NB0XHT3S-N, jvr:-L6C0XPHT-4, jvr:-WK5F724J-1, jvr:-D0F21513-5, jvr:-G30ZJ446-J, jvr:-WZF2ZR3L-B, jvr:-NHL3D2X0-S, jvr:-T2TS0S41-N, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-G7KXQWSR-5 ;
  dc:created "1999-01-01"^^xsd:date ;
  mesh:registryNumber "EC 1.-" ;
  skos:hiddenLabel "EC 1.-"@fr, "EC 1.-"@en ;
  a skos:Concept, mesh:Descriptor ;
  dc:modified "2020-05-27"^^xsd:date ;
  skos:prefLabel "Mixed function oxygenases"@fr, "Mixed Function Oxygenases"@en ;
  skos:definition "Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation."@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D006899> ;
  skos:broader jvr:-VM13B2BD-7 ;
  dc:established "2003-01-01"^^xsd:date ;
  skos:inScheme jvr: .

jvr:-DVHNWMLM-V
  skos:prefLabel "Benzoate 4-monooxygenase"@fr, "Benzoate 4-Monooxygenase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-B91PLTDL-F
  skos:prefLabel "Dopamine beta-Hydroxylase"@en, "Dopamine beta-monooxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-N5WPRGPS-F
  skos:prefLabel "Vitamin K epoxide reductases"@fr, "Vitamin K Epoxide Reductases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-T5CCLCV4-2
  skos:prefLabel "Tryptophan Hydroxylase"@en, "Tryptophane 5-monooxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q6J78B97-Z
  skos:prefLabel "Catechol oxidase"@fr, "Catechol Oxidase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-ZGM7ZWZH-Q
  skos:prefLabel "Procollagen-lysine, 2-oxoglutarate 5-dioxygenase"@fr, "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-VM13B2BD-7
  skos:prefLabel "Oxygenases"@en, "Oxygénases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-CGCP4DFF-R .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CSRVSGPJ-P
  skos:prefLabel "gamma-Butyrobetaine Dioxygenase"@en, "gamma-butyrobetaine dioxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z3D0THLS-4
  skos:prefLabel "Prostaglandin-endoperoxide synthases"@fr, "Prostaglandin-Endoperoxide Synthases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PR5B8C7D-F
  skos:prefLabel "Squalene Monooxygenase"@en, "Squalene monooxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-JPRJH6XQ-G
  skos:prefLabel "Fatty acid desaturases"@fr, "Fatty Acid Desaturases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BH3JH250-T
  skos:prefLabel "Tyrosine 3-Monooxygenase"@en, "Tyrosine 3-monooxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CCPRHMPB-4
  skos:prefLabel "Kynurenine 3-Monooxygenase"@en, "Kynurenine 3-monooxygenase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QW6NM13W-2
  skos:prefLabel "Cytochrome P-450 enzyme system"@fr, "Cytochrome P-450 Enzyme System"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DZJ47ZRM-V
  skos:prefLabel "4-Hydroxybenzoate 3-monooxygenase"@fr, "4-Hydroxybenzoate-3-Monooxygenase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QMN00FPR-M
  skos:prefLabel "Prolyl hydroxylases"@fr, "Prolyl Hydroxylases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-B89T56WP-1
  skos:prefLabel "Phenylalanine 4-monooxygenase"@fr, "Phenylalanine Hydroxylase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-VVJ7SMDH-Q
  skos:prefLabel "Heme oxygenase (decyclizing)"@fr, "Heme Oxygenase (Decyclizing)"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CGCP4DFF-R .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .