@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-W8PJZ9DZ-T
  skos:prefLabel "Phosphatidylinositol-4-phosphate 3-kinase"@fr, "Phosphatidylinositol-4-Phosphate 3-Kinase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CG2RL965-3 .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RZ7ZF59C-G
  skos:prefLabel "Intracellular Signaling Peptides and Proteins"@en, "Protéines et peptides de signalisation intracellulaire"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-CG2RL965-3 .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-KB0T8WCR-0
  skos:prefLabel "Phosphotransferases (Alcohol Group Acceptor)"@fr, "Phosphotransferases (Alcohol Group Acceptor)"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-CG2RL965-3 .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CG2RL965-3
  mesh:allowableQualifier jvr:-WK5F724J-1, jvr:-N2WP45CN-V, jvr:-TJHVZCRZ-0, jvr:-T2TS0S41-N, jvr:-HQRFT0C6-B, jvr:-Q3979798-W, jvr:-BT300B3G-Q, jvr:-NFTHND7Q-8, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-Z9TSGBXH-4, jvr:-CB30NGKB-3, jvr:-THHNVC7V-3, jvr:-W6SQV79N-S, jvr:-NKM836P1-M, jvr:-FWD2BGQ0-9, jvr:-T9HQD7ST-J, jvr:-H7K65Q8S-Z, jvr:-SBNWSM1T-R, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-D0F21513-5, jvr:-NB0XHT3S-N, jvr:-NHL3D2X0-S, jvr:-CJXMKG5Q-F, jvr:-WZF2ZR3L-B, jvr:-S0CS1X5R-5, jvr:-G7KXQWSR-5 ;
  skos:altLabel "PI 3-Kinase"@en, "PI3 Kinases"@en, "Phosphoinositide 3-Hydroxykinase"@en, "Phosphoinositide 3 Kinases"@en, "Phosphatidylinositol-3-OH Kinase"@en, "PI-3 Kinase"@en, "PI3-Kinase"@en, "PI-3K"@en, "PtdIns 3-Kinases"@en, "PtdIns 3-Kinase"@en ;
  dc:established "1998-01-01"^^xsd:date ;
  skos:definition "Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell."@en ;
  mesh:registryNumber "EC 2.7.1.-" ;
  skos:prefLabel "Phosphatidylinositol 3-kinases"@fr, "Phosphatidylinositol 3-Kinases"@en ;
  dc:created "1997-07-02"^^xsd:date ;
  skos:inScheme jvr: ;
  dc:modified "2021-05-21"^^xsd:date ;
  skos:narrower jvr:-FFLWHMDG-J, jvr:-W8PJZ9DZ-T ;
  skos:broader jvr:-KB0T8WCR-0, jvr:-RZ7ZF59C-G ;
  a mesh:Descriptor, skos:Concept ;
  skos:hiddenLabel "EC 2.7.1.-"@fr, "EC 2.7.1.-"@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D019869> .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FFLWHMDG-J
  skos:prefLabel "Phosphatidylinositol 3-kinase"@fr, "Phosphatidylinositol 3-Kinase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-CG2RL965-3 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .