@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-DG3TD8DB-1 skos:prefLabel "Fibrinolytic Agents"@en, "Fibrinolytiques"@fr ; a mesh:Descriptor, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WC7HBM1N-C skos:prefLabel "Plasminogen Activators"@en, "Activateurs du plasminogène"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-C8BHCSFT-7 . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PDMNHKZ3-J skos:prefLabel "Ténectéplase"@fr, "Tenecteplase"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-C8BHCSFT-7 . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-C8BHCSFT-7 mesh:allowableQualifier jvr:-WZF2ZR3L-B, jvr:-D0F21513-5, jvr:-S0CS1X5R-5, jvr:-FWD2BGQ0-9, jvr:-Q3979798-W, jvr:-THHNVC7V-3, jvr:-W6SQV79N-S, jvr:-H7K65Q8S-Z, jvr:-G7KXQWSR-5, jvr:-T9HQD7ST-J, jvr:-WK5F724J-1, jvr:-CB30NGKB-3, jvr:-HQRFT0C6-B, jvr:-G30ZJ446-J, jvr:-N2WP45CN-V, jvr:-CJXMKG5Q-F, jvr:-Z9TSGBXH-4, jvr:-M63HSDM7-1, jvr:-R3QWLHRG-V, jvr:-T2TS0S41-N, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-XV06LPML-W, jvr:-NHL3D2X0-S, jvr:-BT300B3G-Q, jvr:-NB0XHT3S-N, jvr:-SBNWSM1T-R, jvr:-L6C0XPHT-4, jvr:-NFTHND7Q-8 ; skos:prefLabel "Tissue Plasminogen Activator"@en, "Activateur tissulaire du plasminogène"@fr ; a mesh:Descriptor, skos:Concept ; owl:sameAs ; skos:altLabel "t-PA (t-Plasminogen Activator)"@fr, "105857-23-6 (Alteplase)"@en, "105857-23-6 (Alteplase)"@fr, "TTPA"@en, "tPA (tissue Plasminogen Activator)"@fr, "Tisokinase"@en, "Tissue-Type Plasminogen Activator"@en, "Altéplase"@fr, "T-Plasminogen Activator"@en, "Plasminogen Activator, Tissue-Type"@en, "Alteplase"@en, "Tissue Activator D-44"@en ; mesh:registryNumber "EC 3.4.21.68" ; dc:established "1986-01-01"^^xsd:date ; skos:broader jvr:-WC7HBM1N-C ; skos:hiddenLabel "Activase"@fr, "Activase"@en, "Lysatec rt-PA"@en, "Actilyse"@fr, "Actilyse"@en, "EC 3.4.21.68"@en, "EC 3.4.21.68"@fr ; skos:inScheme jvr: ; dc:created "1985-06-12"^^xsd:date ; skos:definition "A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases."@en ; dc:modified "2016-07-01"^^xsd:date ; skos:narrower jvr:-PDMNHKZ3-J ; mesh:pharmacologicalAction jvr:-DG3TD8DB-1 . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .