@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XR6MT7ZV-V skos:prefLabel "Cardiotoniques"@fr, "Cardiotonic Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RR4LR2Z2-M skos:prefLabel "Hétérosides"@fr, "Glycosides"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-C1ZWPH34-6 . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-C1ZWPH34-6 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R, jvr:-RNN9WKG8-L, jvr:-XR6MT7ZV-V ; mesh:allowableQualifier jvr:-THHNVC7V-3, jvr:-NHL3D2X0-S, jvr:-XV06LPML-W, jvr:-TJHVZCRZ-0, jvr:-CB30NGKB-3, jvr:-WK5F724J-1, jvr:-S0CS1X5R-5, jvr:-HQRFT0C6-B, jvr:-T9HQD7ST-J, jvr:-Z9TSGBXH-4, jvr:-R0ZCQ8X6-J, jvr:-NKM836P1-M, jvr:-D0F21513-5, jvr:-G7KXQWSR-5, jvr:-SBNWSM1T-R, jvr:-R3QWLHRG-V, jvr:-G30ZJ446-J, jvr:-M63HSDM7-1, jvr:-H7K65Q8S-Z, jvr:-NB0XHT3S-N, jvr:-W6SQV79N-S, jvr:-BT300B3G-Q, jvr:-Q3979798-W, jvr:-L6C0XPHT-4, jvr:-FWD2BGQ0-9, jvr:-NFTHND7Q-8 ; skos:inScheme jvr: ; skos:broader jvr:-RR4LR2Z2-M, jvr:-ZD8LRK33-P ; dc:created "1999-01-01"^^xsd:date ; skos:definition "Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose."@en ; dc:established "1966-01-01"^^xsd:date ; skos:prefLabel "Cardiac Glycosides"@en, "Glucosides cardiotoniques"@fr ; owl:sameAs ; a skos:Concept, mesh:Descriptor ; skos:altLabel "Cardiotonic Steroid"@en, "Cardiotonic Steroids"@en, "Cardiac Glycoside"@en, "Hétérosides cardiotoniques"@fr ; dc:modified "2020-05-27"^^xsd:date ; skos:narrower jvr:-XWG994LH-T, jvr:-X48GNQFH-M . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-X48GNQFH-M skos:prefLabel "Cardenolides"@en, "Cardénolides"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-C1ZWPH34-6 . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZD8LRK33-P skos:prefLabel "Cardanolides"@en, "Cardanolides"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-C1ZWPH34-6 . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-LS0SSBHQ-R skos:prefLabel "Anti-Arrhythmia Agents"@en, "Antiarythmiques"@fr ; a mesh:Descriptor, skos:Concept . jvr:-RNN9WKG8-L skos:prefLabel "Enzyme Inhibitors"@en, "Antienzymes"@fr ; a mesh:Descriptor, skos:Concept . jvr:-XWG994LH-T skos:prefLabel "Bufanolides"@en, "Bufanolide"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-C1ZWPH34-6 . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .