@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q1MK6QZP-Q skos:prefLabel "Enzymes"@fr, "Enzymes"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-C15MGKVK-S . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XT3C2LT7-0 skos:prefLabel "DNA restriction enzymes"@fr, "DNA Restriction Enzymes"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-C15MGKVK-S . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-ZT2QPDZC-C skos:prefLabel "DNA Modification Methylases"@en, "DNA modification methylases"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-C15MGKVK-S . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-C15MGKVK-S skos:definition "Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage."@en ; mesh:allowableQualifier jvr:-N2WP45CN-V, jvr:-NKM836P1-M, jvr:-THHNVC7V-3, jvr:-NFTHND7Q-8, jvr:-HQRFT0C6-B, jvr:-T2TS0S41-N, jvr:-D0F21513-5, jvr:-CB30NGKB-3, jvr:-NB0XHT3S-N, jvr:-TJHVZCRZ-0, jvr:-H7K65Q8S-Z, jvr:-L6C0XPHT-4, jvr:-WZF2ZR3L-B, jvr:-BT300B3G-Q, jvr:-CJXMKG5Q-F, jvr:-WK5F724J-1, jvr:-S0CS1X5R-5, jvr:-T9HQD7ST-J, jvr:-FWD2BGQ0-9, jvr:-NHL3D2X0-S, jvr:-G30ZJ446-J, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-Q3979798-W, jvr:-Z9TSGBXH-4, jvr:-G7KXQWSR-5, jvr:-SBNWSM1T-R ; skos:altLabel "Restriction Modification System"@en, "DNA Restriction Modification Enzymes"@en, "DNA Restriction Modification Enzyme"@en, "Restriction-Modification System"@en, "DNA Restriction-Modification Enzyme"@en, "Restriction Modification Systems"@en, "Restriction-Modification Systems"@en ; skos:inScheme jvr: ; owl:sameAs ; skos:prefLabel "DNA Restriction-Modification Enzymes"@en, "Enzymes de restriction-modification de l'ADN"@fr ; skos:narrower jvr:-ZT2QPDZC-C, jvr:-XT3C2LT7-0 ; dc:created "1988-05-23"^^xsd:date ; dc:modified "2020-05-27"^^xsd:date ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-Q1MK6QZP-Q ; dc:established "1989-01-01"^^xsd:date . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .