@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-CX5RBXXG-B
  skos:prefLabel "Maturation post-traductionnelle des protéines"@fr, "Protein Processing, Post-Translational"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-BZMKW30V-G .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-XS73G4XH-9
  skos:prefLabel "Endoplasmic Reticulum Stress"@en, "Stress du réticulum endoplasmique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-BZMKW30V-G .

jvr:-B4BQBNPV-1
  skos:prefLabel "Dégradation associée au réticulum endoplasmique"@fr, "Endoplasmic Reticulum-Associated Degradation"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-BZMKW30V-G .

jvr:-G66762N6-2
  skos:prefLabel "Dépliement des protéines"@fr, "Protein Unfolding"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-BZMKW30V-G .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-BZMKW30V-G
  owl:sameAs <http://id.nlm.nih.gov/mesh/D056811> ;
  mesh:allowableQualifier jvr:-WZF2ZR3L-B, jvr:-N2WP45CN-V, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-S0CS1X5R-5 ;
  a skos:Concept, mesh:Descriptor ;
  dc:established "2010-01-01"^^xsd:date ;
  skos:inScheme jvr: ;
  skos:related jvr:-G66762N6-2, jvr:-XS73G4XH-9 ;
  skos:altLabel "Réponse aux protéines mal conformées"@fr, "Réponse aux protéines dépliées"@fr ;
  skos:prefLabel "Unfolded Protein Response"@en, "Réponse aux protéines mal repliées"@fr ;
  skos:broader jvr:-CX5RBXXG-B ;
  skos:definition "A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS."@en ;
  skos:narrower jvr:-B4BQBNPV-1 ;
  dc:created "2009-07-06"^^xsd:date ;
  dc:modified "2016-07-01"^^xsd:date .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .