@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BZM9VDXX-3 mesh:allowableQualifier jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R, jvr:-G7KXQWSR-5, jvr:-R3QWLHRG-V, jvr:-BT300B3G-Q, jvr:-NFTHND7Q-8, jvr:-W6SQV79N-S, jvr:-CJXMKG5Q-F, jvr:-T2TS0S41-N, jvr:-XV06LPML-W, jvr:-D0F21513-5, jvr:-T9HQD7ST-J, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-FWD2BGQ0-9, jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-N2WP45CN-V, jvr:-Z9TSGBXH-4, jvr:-HQRFT0C6-B, jvr:-NB0XHT3S-N, jvr:-G30ZJ446-J, jvr:-WZF2ZR3L-B, jvr:-THHNVC7V-3, jvr:-H7K65Q8S-Z, jvr:-S0CS1X5R-5, jvr:-M63HSDM7-1, jvr:-TJHVZCRZ-0, jvr:-L6C0XPHT-4 ; skos:altLabel "Lysine-Ketoglutarate Reductase"@en, "Saccharopine Dehydrogenase"@en, "Saccharopine déshydrogénases"@fr ; skos:hiddenLabel "EC 1.5.1.10"@fr, "EC 1.5.1.10"@en, "EC 1.5.1.8"@fr, "EC 1.5.1.8"@en, "Saccharopine Dehydrogenase (NADP+, L-Lysine Forming)"@en, "Saccharopine Dehydrogenase (NAD+, L-Glutamate Forming)"@en, "Lysine-2-Oxoglutarate Reductase"@en, "EC 1.5.1.7"@fr, "EC 1.5.1.7"@en, "Saccharopine Dehydrogenase (NAD+, L-Lysine Forming)"@en, "EC 1.5.1.-"@fr, "EC 1.5.1.-"@en, "Saccharopine Dehydrogenase (NADP+, L-Glutamate Forming)"@en, "EC 1.5.1.9"@fr, "EC 1.5.1.9"@en ; skos:prefLabel "Saccharopine dehydrogenases"@fr, "Saccharopine Dehydrogenases"@en ; dc:established "1991-01-01"^^xsd:date ; mesh:registryNumber "EC 1.5.1.-", "EC 1.5.1.7", "EC 1.5.1.10", "EC 1.5.1.9", "EC 1.5.1.8" ; owl:sameAs ; dc:created "1974-11-19"^^xsd:date ; skos:related jvr:-W31VDHCQ-3 ; skos:definition "Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS."@en ; skos:inScheme jvr: ; skos:broader jvr:-K476NRX7-N ; dc:modified "2021-06-30"^^xsd:date ; a mesh:Descriptor, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-W31VDHCQ-3 skos:prefLabel "Hyperlysinemias"@en, "Hyperlysinémies"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-BZM9VDXX-3 . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-K476NRX7-N skos:prefLabel "Oxidoreductases Acting on CH-NH Group Donors"@en, "Oxidoreductases acting on CH-NH group donors"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-BZM9VDXX-3 . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .