@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DSTR114N-6
  skos:prefLabel "Isoxazoles"@fr, "Isoxazoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-BPRQC709-L .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DPB2JZPS-T
  skos:prefLabel "Antagonistes des récepteurs 5-HT2 de la sérotonine"@fr, "Serotonin 5-HT2 Receptor Antagonists"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWBNGBWP-4
  skos:prefLabel "Pyrimidines"@fr, "Pyrimidines"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-BPRQC709-L .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-BPRQC709-L
  mesh:allowableQualifier jvr:-HQRFT0C6-B, jvr:-T9HQD7ST-J, jvr:-XV06LPML-W, jvr:-NKM836P1-M, jvr:-THHNVC7V-3, jvr:-NHL3D2X0-S, jvr:-TJHVZCRZ-0, jvr:-W6SQV79N-S, jvr:-R0ZCQ8X6-J, jvr:-FWD2BGQ0-9, jvr:-Q3979798-W, jvr:-H7K65Q8S-Z, jvr:-CB30NGKB-3, jvr:-R3QWLHRG-V, jvr:-NFTHND7Q-8, jvr:-G4R176S9-J, jvr:-M63HSDM7-1, jvr:-WK5F724J-1, jvr:-D0F21513-5, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-SBNWSM1T-R, jvr:-S0CS1X5R-5, jvr:-NB0XHT3S-N, jvr:-BT300B3G-Q ;
  skos:hiddenLabel "R 76477"@en, "Palipéridone"@fr, "Paliperidone"@en, "9-Hydroxy-rispéridone"@fr, "Invega Sustenna"@en, "3-(2-(4-(6-fluoro-3-(1,2-benzisoxazolyl))-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one"@en, "R76477"@fr, "9-Hydroxyrisperidone"@en, "9-Hydroxy-risperidone"@en, "Invega"@en, "R-76477"@fr, "R-76477"@en, "9-OH-risperidone"@en, "9-Hydroxyrispéridone"@fr ;
  skos:broader jvr:-DSTR114N-6, jvr:-FWBNGBWP-4 ;
  skos:inScheme jvr: ;
  dc:established "2016-01-01"^^xsd:date ;
  skos:prefLabel "Paliperidone Palmitate"@en, "Palmitate de palipéridone"@fr ;
  skos:definition "A benzisoxazole derivative and active metabolite of RISPERIDONE that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST and SEROTONIN 5-HT2 RECEPTOR ANTAGONIST. It is an ANTIPSYCHOTIC AGENT used in the treatment of SCHIZOPHRENIA."@en ;
  mesh:pharmacologicalAction jvr:-DPB2JZPS-T, jvr:-FRV1PNZN-9, jvr:-PRPPKQT3-0 ;
  skos:altLabel "199739-10-1 (paliperidone palmitate)"@en, "199739-10-1 (paliperidone palmitate)"@fr, "R8P8USM8FR"@en, "R8P8USM8FR"@fr, "838F01T721"@fr, "838F01T721"@en ;
  dc:created "2015-07-06"^^xsd:date ;
  dc:modified "2016-05-31"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000068882> .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PRPPKQT3-0
  skos:prefLabel "Antagonistes du récepteur D2 de la dopamine"@fr, "Dopamine D2 Receptor Antagonists"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FRV1PNZN-9
  skos:prefLabel "Antipsychotic Agents"@en, "Neuroleptiques"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .