@prefix c0x: <http://data.loterre.fr/ark:/67375/C0X> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc11: <http://purl.org/dc/elements/1.1/> .

c0x:-ZS5G50N5-R
  skos:prefLabel "Janus kinase"@en, "Janus kinase"@fr ;
  a skos:Concept ;
  skos:narrower c0x:-T5GJN8Z0-D .

c0x:-T5GJN8Z0-D
  skos:altLabel "non-receptor tyrosine-protein kinase TYK2"@fr, "TYK2"@en, "TYK2"@fr, "non receptor tyrosine protein kinase tyk2"@en, "kinase TYK2"@fr ;
  skos:broader c0x:-ZS5G50N5-R ;
  skos:prefLabel "tyrosine kinase 2"@en, "tyrosine kinase 2"@fr ;
  skos:exactMatch <https://en.wikipedia.org/wiki/Tyrosine_kinase>, <https://fr.wikipedia.org/wiki/Tyrosine_kinase> ;
  skos:inScheme c0x: ;
  skos:definition """Une tyrosine kinase est une transférase qui catalyse la réaction chimique : ATP + L-tyrosine-[protéine] ⇌ {\\\\displaystyle \\
ightleftharpoons } \\
ightleftharpoons O-phospho-L-tyrosine-[protéine] + ADP. Ces enzymes agissent comme des « interrupteurs » d'activation ou d'inhibition de nombreuses fonctions cellulaires. (Wikipédia)"""@fr, "A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as an \"on\" or \"off\" switch in many cellular functions. Tyrosine kinases belong to a larger class of enzymes known as protein kinases which also attach phosphates to other amino acids such as serine and threonine. Phosphorylation of proteins by kinases is an important mechanism for communicating signals within a cell (signal transduction) and regulating cellular activity, such as cell division. (Wikipedia)"@en ;
  dc11:creator "Patricia Fener" ;
  a skos:Concept .

c0x: a skos:ConceptScheme .