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Concept information

process > neurophysiological process > long-term potentiation

Preferred term

long-term potentiation  

Definition

  • Process resulting in long-lasting increase in synapse efficiency (a few hours to several weeks) after a series of high-frequency electrical stimulation.

Broader concept

Related concepts

Synonym(s)

  • long-term synaptic potentiation
  • LTP

Belongs to group

Bibliographic citation(s)

  • • Bliss, T. V., & Lømo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. The Journal of Physiology, 232(2), 331–356. https://doi.org/10.1113/jphysiol.1973.sp010274

    • Document type: empirical study

    • Access: closed

  • • Lømo, T. (1966). Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation. Acta Physiologica Scandinavica, 68 (Suppl 277), 128.

    • Document type: empirical study

    • Access: closed

  • • Lømo, T. (2018). Discovering long‐term potentiation (LTP) – recollections and reflections on what came after. Acta Physiologica, 222(2), 1–1. https://doi.org/10.1111/apha.12921

    • Document type: historical study

    , literature review

    • Access: closed

  • • Nicoll, R. A. (2017). A brief history of long-term potentiation. Neuron, 93(2), 281–290. https://doi.org/10.1016/j.neuron.2016.12.015

    • Document type: historical study

    • Access: open

Creator

  • Frank Arnould

In other languages

URI

http://data.loterre.fr/ark:/67375/P66-NG7QTM2N-0

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