Concept information
Terme préférentiel
Genes, erbB-2
Type
-
mesh:Descriptor
Définition
- The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Concept générique
Synonyme(s)
- c-erbB-2 Genes
- c-erbB-2 Proto-Oncogenes
- erbB-2 Genes
- Genes, erbb2
- Genes, HER-2
- Genes, HER2
- Genes, neu
Qualificatif(s) autorisé(s)
Traductions
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français
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Gène erbB-2
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Gènes c-erbB-2
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Gènes erbb2
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Gènes HER-2
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Gènes HER2
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Gènes neu
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Proto-oncogène c-erbB-2
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Proto-oncogènes c-erbB-2
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Protooncogènes c-erbB-2
URI
http://data.loterre.fr/ark:/67375/JVR-Z3RC22R0-1
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