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Concept information

Cells > Giant Cells

Terme préférentiel

Giant Cells  

Type

  • mesh:Descriptor

Définition

  • Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.

Concept générique

Synonyme(s)

  • Giant Cells, Multinucleated
  • Multinucleated Giant Cells
  • Polykaryocytes
  • Syncytia
  • Syncytium

Traductions

  • français

  • Cellule géante
  • Cellules géantes multinucléées
  • Cellules géantes plurinucléées
  • Plasmodes
  • Polycaryocyte
  • Polycaryocytes
  • Syncytium cellulaire
  • Syncytiums cellulaires

URI

http://data.loterre.fr/ark:/67375/JVR-Z2XBB964-5

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RDF/XML TURTLE JSON-LD Date de création 07/04/1989, dernière modification le 24/06/2011