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Concept information

... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Fatty Acids, Monounsaturated > Cilastatin > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Alicyclic > Cycloparaffins > Cyclopropanes > Cilastatin > Cilastatin, Imipenem Drug Combination
... > Polycyclic Compounds > Macrocyclic Compounds > Cycloparaffins > Cyclopropanes > Cilastatin > Cilastatin, Imipenem Drug Combination
Pharmaceutical Preparations > Drug Combinations > Cilastatin, Imipenem Drug Combination
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Inorganic Chemicals > Sulfur Compounds > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Sulfur Compounds > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination
... > Organic Chemicals > Amides > Lactams > beta-Lactams > Carbapenems > Thienamycins > Imipenem > Cilastatin, Imipenem Drug Combination

Terme préférentiel

Cilastatin, Imipenem Drug Combination  

Type

  • mesh:Descriptor

Définition

  • Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.

Concept générique

Synonyme(s)

  • 85960-17-4 (Na salt)
  • 92309-29-0
  • Imipenem - Cilastatin
  • Imipenem Cilastatin
  • Imipenem-Cilastatin

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-Z0J5X092-J

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RDF/XML TURTLE JSON-LD Date de création 09/07/2018, dernière modification le 10/04/2018