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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Cytoadhesin > Integrin alpha6beta4
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Laminin > Integrin alpha6beta4

Terme préférentiel

Integrin alpha6beta4  

Type

  • mesh:Descriptor

Définition

  • This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.

Concept générique

Concepts associés

Synonyme(s)

  • A9 Antigen
  • alpha(6)beta(4) Epithelial Integrin
  • alpha6 beta4 Integrin
  • alpha(6)beta(4) Integrin
  • Integrin alpha(6),beta(4)
  • Laminin-5 Receptor (alpha6beta4 Integrin)
  • TSP-180
  • Tumor Specific Protein-180 Complex

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-X3GM637Q-5

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RDF/XML TURTLE JSON-LD Date de création 02/07/2002, dernière modification le 09/07/2013