Passer au contenu principal

Medical Subject Headings (thesaurus)

Choisissez le vocabulaire dans lequel chercher

  • Aide
aligner
annoter
télécharger

Concept information

Genetic Phenomena > Genetic Variation > Mutation > Mutagenesis, Insertional
Genetic Phenomena > Mutagenesis > Mutagenesis, Insertional
Investigative Techniques > Genetic Techniques > Genetic Engineering > Protein Engineering > Mutagenesis, Insertional

Terme préférentiel

Mutagenesis, Insertional  

Type

  • mesh:Descriptor

Définition

  • Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.

Concept générique

Concepts associés

Synonyme(s)

  • Insertional Mutagenesis

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-WN4NR7JK-S

Télécharger ce concept :

RDF/XML TURTLE JSON-LD Date de création 29/05/1990, dernière modification le 29/06/2018