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... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Oncogenes > Proto-Oncogenes > Genes, erbB > Genes, erbB-1

Terme préférentiel

Genes, erbB-1  

Type

  • mesh:Descriptor

Définition

  • The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.

Concept générique

Concepts associés

Synonyme(s)

  • erbB-1 Genes
  • Genes, erbB1

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-WHHNH96P-C

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RDF/XML TURTLE JSON-LD Date de création 23/05/1994, dernière modification le 02/07/2018