Concept information
Terme préférentiel
Receptors, Leptin
Type
-
mesh:Descriptor
Définition
- Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage. Isoform A is expressed in fetal liver, hematopoietic tissues, and choroid plexus. Isoform B is highly expressed in hypothalamus.
Concept générique
Synonyme(s)
- Antigens, CD295
- CD295 Antigens
- LEPR Protein
- Leptin-Binding Protein
- Leptin Receptor
- Leptin Receptors
- OB Receptor
- Receptor, Leptin
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
Traductions
-
français
-
Antigène CD295
-
Protéine de liaison à la leptine
-
Protéine LEPR
-
Récepteur à la leptine
-
Récepteur Ob
-
Récepteurs de la leptine
URI
http://data.loterre.fr/ark:/67375/JVR-W5J4NWRX-X
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