Concept information
Terme préférentiel
APOBEC-3G Deaminase
Type
-
mesh:Descriptor
Définition
- An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
Concept générique
Synonyme(s)
- APOBEC-3G dC-dU Editing Enzyme
- APOBEC3G Deaminase
- APOBEC-3G Protein
- APOBEC3G Protein
- APOBEC-Related Cytidine Deaminase
- APOBEC-Related Protein
- CEM15 Protein
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
APOBEC-3G dC-dU editing enzyme
-
Cytidine désaminase apparentée aux APOBEC
-
Désaminase APOBEC-3G
-
Désaminase APOBEC3G
-
Protéine APOBEC-3G
-
Protéine apparentée aux APOBEC
-
Protéine CEM15
URI
http://data.loterre.fr/ark:/67375/JVR-VPD0CKZN-S
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