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Concept information

Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 4 or More Rings > Rifamycins > Rifampin
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams > Lactams, Macrocyclic > Rifamycins > Rifampin
... > Organic Chemicals > Amides > Lactams > Lactams, Macrocyclic > Rifamycins > Rifampin
Polycyclic Compounds > Macrocyclic Compounds > Lactams, Macrocyclic > Rifamycins > Rifampin

Terme préférentiel

Rifampin  

Type

  • mesh:Descriptor

Définition

  • A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)

Concept générique

Synonyme(s)

  • 13292-46-1 (Rifampin)
  • Benemycin
  • Rifampicin
  • Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
  • VJT6J7R4TR

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Rifampicine

    français

  • 13292-46-1 (Rifampin)
  • Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
  • VJT6J7R4TR

URI

http://data.loterre.fr/ark:/67375/JVR-TNC366H5-P

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 31/05/2016