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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein L2
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein L2

Terme préférentiel

Forkhead Box Protein L2  

Type

  • mesh:Descriptor

Définition

  • A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).

Concept générique

Synonyme(s)

  • Forkhead Box L2 Protein
  • FOXL2 Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-TKDWQ8ND-W

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 22/05/2017