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Concept information

Terme préférentiel

RNA-Induced Silencing Complex  

Type

  • mesh:Descriptor

Définition

  • A multicomponent, ribonucleoprotein complex comprised of one of the family of ARGONAUTE PROTEINS and the "guide strand" of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating gene expression are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA).

Concepts spécifiques

Synonyme(s)

  • RISC Multicomponent Nuclease

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-SWSBWS2L-W

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RDF/XML TURTLE JSON-LD Date de création 03/07/2002, dernière modification le 24/06/2011