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Concept information

... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Complement Factor I
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Complement Factor I
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Complement Inactivator Proteins > Complement C3b Inactivator Proteins > Complement Factor I

Terme préférentiel

Complement Factor I  

Type

  • mesh:Descriptor

Définition

  • A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.

Concept générique

Synonyme(s)

  • C3b-C4b Inactivator
  • C3b Inactivator
  • C4b-C3b-INA
  • C4bC3bINA
  • Complement 3b-Complement 4b Inactivator
  • Complement C4b-C3b Inactivator

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Facteur I du complément

    français

  • Inactivateur C3b-C4b
  • Inactivateur des fragments C3b-C4b du complément
  • Inactivateur du C3b

URI

http://data.loterre.fr/ark:/67375/JVR-SL6DCZDS-1

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RDF/XML TURTLE JSON-LD Date de création 07/05/1992, dernière modification le 06/07/2009