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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > Chromosomal Proteins, Non-Histone > CCCTC-Binding Factor
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Chromosomal Proteins, Non-Histone > CCCTC-Binding Factor

Terme préférentiel

CCCTC-Binding Factor  

Type

  • mesh:Descriptor

Définition

  • A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.

Concept générique

Synonyme(s)

  • CTCF Protein
  • DNA-Binding Protein CTCF

Qualificatif(s) autorisé(s)

Traductions

  • Facteur de liaison à la séquence CCCTC

    français

  • Facteur se fixant à la séquence CCCTC
  • Facteur se liant à la séquence CCCTC
  • Protéine CTCF
  • Protéine CTCF de liaison à l'ADN
  • Protéine CTCF se fixant à l'ADN
  • Protéine CTCF se liant à l'ADN

URI

http://data.loterre.fr/ark:/67375/JVR-SKJD27C9-T

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 29/06/2017