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Concept information

... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Oncogenes

Terme préférentiel

Oncogenes  

Type

  • mesh:Descriptor

Définition

  • Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.

Concept générique

Concepts spécifiques

Synonyme(s)

  • Oncogene
  • Transforming Gene
  • Transforming Genes

Qualificatif(s) autorisé(s)

Traductions

  • Oncogènes

    français

  • Gènes transformants
  • Oncogène

URI

http://data.loterre.fr/ark:/67375/JVR-S1L8LZQ9-2

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RDF/XML TURTLE JSON-LD Date de création 22/04/1982, dernière modification le 08/07/2008