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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Fanconi Anemia Complementation Group Proteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > BRCA1 Protein

Terme préférentiel

BRCA1 Protein  

Type

  • mesh:Descriptor

Définition

  • The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)

Concept générique

Concepts associés

Synonyme(s)

  • BRCA1 Gene Product
  • Breast Cancer 1 Gene Product
  • Breast Cancer 1 Protein
  • Breast Cancer Type 1 Susceptibility Protein
  • Ring Finger Protein 53

Qualificatif(s) autorisé(s)

Traductions

  • Protéine BRCA1

    français

  • Produit du gène BRCA1
  • Produit du gène-1 du cancer du sein
  • Protéine-1 du cancer du sein

URI

http://data.loterre.fr/ark:/67375/JVR-RVD05M67-L

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RDF/XML TURTLE JSON-LD Date de création 10/06/1996, dernière modification le 23/11/2015