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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Lipoproteins > Apolipoproteins > Apolipoproteins E > Apolipoprotein E2
Lipids > Lipoproteins > Apolipoproteins > Apolipoproteins E > Apolipoprotein E2
... > Amino Acids, Peptides, and Proteins > Proteins > Apoproteins > Apolipoproteins > Apolipoproteins E > Apolipoprotein E2

Terme préférentiel

Apolipoprotein E2  

Type

  • mesh:Descriptor

Définition

  • One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III.

Concept générique

Synonyme(s)

  • Apo E-2
  • Apo E2
  • ApoE2
  • APOE-epsilon 2
  • APOE-epsilon2
  • Apolipoprotein E-2
  • Apolipoprotein E-epsilon2

Qualificatif(s) autorisé(s)

Traductions

  • Apolipoprotéine E2

    français

  • Apo E-2
  • Apo E2
  • APOE-epsilon 2
  • APOE-epsilon2
  • ApoE2
  • Apolipoprotéine de type E2
  • Apolipoprotéine epsilon E2

URI

http://data.loterre.fr/ark:/67375/JVR-RDDLTVCF-K

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RDF/XML TURTLE JSON-LD Date de création 05/07/2006