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Concept information

... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Eicosanoids > Arachidonic Acids > Hydroxyeicosatetraenoic Acids > 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
... > Biological Factors > Inflammation Mediators > Autacoids > Eicosanoids > Arachidonic Acids > Hydroxyeicosatetraenoic Acids > 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Fatty Acids, Essential > Arachidonic Acids > Hydroxyeicosatetraenoic Acids > 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

Terme préférentiel

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid  

Type

  • mesh:Descriptor

Définition

  • A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

Concept générique

Synonyme(s)

  • 12-HETE
  • 59985-28-3

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-R7P19PP9-G

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RDF/XML TURTLE JSON-LD Date de création 10/06/1996, dernière modification le 22/06/2015