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Concept information

Terme préférentiel

Tensins  

Type

  • mesh:Descriptor

Définition

  • A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.

Concept générique

Synonyme(s)

  • Tensin

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-PWL71CNT-X

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RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 26/02/2016