Concept information
Terme préférentiel
Dapsone
Type
-
mesh:Descriptor
Définition
- A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Concept générique
Concepts spécifiques
Synonyme(s)
- 4,4'-Diaminophenyl Sulfone
- 80-08-0 (Dapsone)
- 8W5C518302
- DADPS
- Diaminodiphenylsulfone
- Diaphenylsulfone
- Sulfonyldianiline
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
4,4'-Diaminodiphénylsulfone
-
80-08-0 (Dapsone)
-
8W5C518302
URI
http://data.loterre.fr/ark:/67375/JVR-P611DVD2-V
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