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Concept information

Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases

Terme préférentiel

Caspases  

Type

  • mesh:Descriptor

Définition

  • A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.

Concept générique

Concepts spécifiques

Concepts associés

Synonyme(s)

  • Caspase

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-P073TW3D-8

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RDF/XML TURTLE JSON-LD Date de création 10/06/1998, dernière modification le 21/05/2021