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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Subunits > Immunoglobulin J-Chains

Terme préférentiel

Immunoglobulin J-Chains  

Type

  • mesh:Descriptor

Définition

  • A 15 kDa "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.

Concept générique

Concepts associés

Synonyme(s)

  • Ig J Chains
  • Ig J-Peptide
  • Immunoglobulin J-Peptide
  • Immunoglobulin J Polypeptide
  • J-Chains, Immunoglobulin

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

  • Chaines J des immunoglobulines

    français

  • Chaines de jonction des Ig
  • Chaines de jonction des immunoglobulines
  • Chaines J d'immunoglobulines
  • Chaînes J des immunoglobulines
  • Peptide J
  • Pièce intermédiaire J

URI

http://data.loterre.fr/ark:/67375/JVR-MTRMC5NG-C

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 02/07/2019